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Use caution in patients with a history of reactions to other GLP-1 agonists

These side effects are typical for this class of drugs and often subside over time

This means that they do come with risks and side effects, as mentioned in the treatment descriptions above

COX is needed to convert arachidonic acid to prostaglandin H2 (PGH2) in the body

To a prediabetic, that shift can reduce the likelihood of progressing to full blown glucose dysregulation