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Jelsing J, Vrang N, Hansen G, Ravn K, Tang-Christensen M, Knudsen LB

In conclusion, this study demonstrates for the first time that semaglutide can maintain normal neurocytoskeletal structure, promote axonal growth and neurogenesis by downregulating the phosphorylation of HTT Ser 1843 and NEFH Ser 661 , and upregulating the phosphorylation of NEFL Ser 473 thereby reducing the risk of developing obesity-induced cognitive impairment

Many clinical trial participants experienced 15-20% body weight reduction by this stage
However, it has quickly gained widespread recognition for its powerful effects on weight loss

"Tirzepatide may lower LDL cholesterol and enhance lipid profiles, particularly at 15 mg and in those with metabolic risk, though study variability and short follow-ups limit firm conclusions," Isaac Hong from the Faculty of Medicine, University of Costa Rica, and colleagues wrote

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