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The underlying mechanism for increased heart rate remains to be elucidated but is hypothesized to be related to a direct effect at the sinus node and/or stimulation of the sympathetic nervous system, with this effect related to the duration of action of the respective GLP-1RAs (Lorenz et al

For example, the GLP-1s Saxenda or Victoza (liraglutide) have been found to improve fertility, especially among people with PCOS
(iv) compound structures (for small molecule drugs)

17 Long-term effects of GLP-1 in animal studies demonstrated increases in beta-cell mass and beta-cell efficiency

By Lauren Arcuri Glucagon-like peptide-1 (GLP-1) receptor agonist drugs such as semaglutide and tirzepatide were originally developed to treat type 2 diabetes
