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[32] [33] Off-label medications with evidence supporting their use include other SSRIs and serotonin-norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine and desvenlafaxine, gabapentin, and oxybutynin (with caution regarding anticholinergic side effects)

Importantly, comorbid T2DM or elevated peripheral IR accelerate disease progression in AD and PD independently of vascular disease, with higher peripheral IR predicting conversion from mild cognitive impairment to AD (12, 13) and faster motor and cognitive decline in PD (14, 15), thereby implicating IR as a modifier of NDD biology rather than a simple comorbidity

The gut-brain axis works both waysjust as gut bacteria influence brain function, stress and emotions can significantly impact gut health and hormone production

When combined with interventions that support metabolic resilience, cellular maintenance, and behavioral stability, they may contribute to maintaining physiological function over time

Follow your healthcare providers recommended dosages to ensure safe and effective medication use

Para quienes ya tienen recetados medicamentos GLP-1 como Mounjaro, es fundamental rotar los puntos de inyeccin