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In Graves disease, where extrathyroidal manifestations are mediated by TSHR/IGF-1R-expressing fibroblasts, studies could test GLP-1RAs as adjuncts to antithyroid drugs or biologics (for example, alongside IGF-1R blockade for orbitopathy) to reduce systemic inflammation and metabolic drivers without compromising disease control [19,25,67]

Patients who travel frequently: Injectable GLP-1 medications require cold-chain storage, sharps containers, and the logistics of traveling with needles and vials

10.1016/j.bbrc.2018.03.142 12 ChenX.ZhaoP.WangW.GuoL.PanQ

Another use of GLP-1RA is also under study in ELAD (121), a phase II b clinical trial to provide strong evidence in using GLP-1RA as neuroprotective agents against Alzheimers Disease

Effect of Dipeptidyl Peptidase-4 Inhibitors on Heart Failure: A Network Meta-Analysis

In silico screening of potent inhibitors against COVID-19 key targets from a library of FDA-approved drugs