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4e), inguinal WAT (Fig
Patients with severe kidney disease (eGFR below 2030) Patients with recurrent UTIs or fungal infections Type 1 diabetes patients (unless specifically prescribed) Pregnant women References: Protective Influence of SGLT-2 Inhibitors Against Heart Failure PMC 2024 Clinical Evidence for Cardiovascular & Kidney Benefits PMC SGLT2 Inhibitors: Antidiabetic and Cardioprotective Effects PMC Emerging Horizons: SGLT-2 Inhibitors Beyond Diabetes PMC DPP-4 inhibitors, sulfonylureas, TZDs So far we have covered the star players Metformin, GLP-1 agonists, and SGLT2 inhibitors

October 15, 2025: 133 New Lawsuits Filed for Injuries from Zepbound and Other GLP-1 Drugs Between September and October 2025, 133 lawsuits joined the group litigation for people harmed by Zepbound and other GLP-1 drugs

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Length of treatment and patient adherence to taking medication are also important
