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gut microbes glp-1 activity link Effects of receptor agonist on changes in the bacterium and the underlying mechanisms Metabolic control by the microbiome
Description
Gupta S, Sen U

Data obtained in animal models support the idea that GLP-1 reduces sympathoexcitation and induces natriuresis, both processes associated with hypertension

February 6, 2023

The pathophysiology is thought to involve increased sensitivity to cholecystokinin (CCK), leading to excessive gallbladder contractility

*FOR ORAL SEMAGLUTIDE USED FOR TYPE 2 DIABETES SOURCE: American Diabetes Association

GLP-1R expression has also been demonstrated in the central nervous system 45 (CNS), but it is unlikely that such a large molecule as MEDI4166 can efficiently cross the blood brain barrier
