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Glucagon activation increases energy expenditure and promotes fat oxidation, something semaglutide cannot do
NONCLINICAL TOXICOLOGY Carcinogenesis, Mutagenesis, Impairment of Fertility In a 2-year carcinogenicity study in CD-1 mice, subcutaneous doses of 0.3, 1, and 3 mg/kg/day (2-, 8-, and 22fold the maximum recommended human dose [MRHD] of 2.4 mg/week, based on AUC) were administered to the males, and 0.1, 0.3, and 1 mg/kg/day (0.6-, 2-, and 5-fold MRHD) were administered to the females
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People with cystic fibrosis also have a high risk of pancreatic damage and pancreatic insufficiency
