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Description
The primary endpoint was total body weight loss percentage (TBWL%) at 12 months
Aims/hypothesis Insulitis, a hallmark of inflammation preceding autoimmune type 1 diabetes, leads to the eventual loss of functional beta cells
GLP-1 medications like tirzepatide drive rapid weight loss, but muscle tissue can decline alongside fat
A systematic review and meta-analysis was conducted to synthesize the available data from clinical trials and assess the safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes (T2D) and obesity
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