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Diabetic Retinopathy: In individuals with diabetes, rapid improvements in blood sugar controlsometimes seen with GLP-1 drugscan exacerbate diabetic retinopathy, a condition that damages the blood vessels in the retina

Addressing obesity through weight management strategies, including pharmacologic ones like GLP-1 receptor agonists, is a key component of reducing all operative risks, improving surgical outcomes, and enhancing the long-term success of orthopedic interventions

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Some research has raised concerns about potential negative effects on insulin sensitivity and liver fat with long-term use

The transient receptor potential channel TRPA1: from gene to pathophysiology