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Originally marketed for treating Type 2 diabetes, Ozempicperhaps the most popular of the injectable medications called semaglutide that was FDA-approved in 2017has become the weight loss trend

However, many anti-obesity agents that have entered human clinical trials have shown unacceptable adverse events

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This pattern reflects the drug's mechanism: semaglutide works by regulating appetite hormones and metabolic signals, so discontinuation removes that biological support unless lifestyle modifications have produced durable metabolic change

Ensayo aleatorizado, doble ciego y controlado con placebo, n=338 participantes, con escalado progresivo de dosis cada cuatro semanas