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Avoid inulin, FOS, and high doses of prebiotic fibers during diarrhea episodes

Nat Med 30:20582066 Bakris GL, Agarwal R, Anker SD, for the FIDELIO-DKD Investigators et al (2020) Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes

Limited adoption stems largely from injection requirements and high costsbarriers an oral drug could overcome

We used mean changes from the time of drug discontinuation to the specified cutoff point of follow-up (week 4, week 8, week 12, week 20, week 26, and week 52) and standard deviations (SDs) extracted from published data when reported

Beyond metabolic disease, these multifunctional agonists have the potential to treat diseases where targeted medicinal action is preferred over systematic administration, as demonstrated with the GLP-1/oestrogen conjugate

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