when were glp 1 agonists discovered A timeline of GLP- discovery and clinical development. Created in PDB-101: Molecule of the Month:
Description
These drugs mimic the effects of the naturally occurring GLP-1 hormone, which is produced in the small intestine and plays a crucial role in regulating insulin secretion, glucose homeostasis, and appetite

Dennis JM, Young KG, Cardoso P, Gudemann LM, McGovern AP, Farmer A, et al

Evaluating drug cost per responder and number needed to treat associated with lixisenatide on top of glargine when compared to rapid-acting insulin intensification regimens on top of glargine, in patients with type 2 diabetes in the UK, Italy, and Spain

Additionally, pressure to cover GLP-1s could become a hot-button issue for private market and employer-sponsored plans

For more on what to expect over time, the guide on semaglutide results week by week tracks the full progression of changes

Will I definitely lose weight on a GLP-1 medication
