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In a separate trial, ACHIEVE-5, the therapy reduced A1C by 1.9 percent compared with 0.8 percent for placebo, alongside weight loss and improvements in #cardiovascular risk factors

doi:10.1016/j.pnpbp.2018.12.014

But for others, its the opposite

[2] [4] Hypoglycaemia: Causes and Risk Factors Hypoglycaemia refers to abnormally low blood glucose levels, typically defined as below 4.0 mmol/L, though symptoms can occur at higher levels in some individuals

Materials and methods This study was designed following the framework delineated by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [17] with rigorous attention given to registering the study protocol in the International Prospective Register for Systematic Reviews (PROSPERO) (registration code: CRD42023466256)

Flatulence is generally less frequent than other GI effects, while diarrhea has been reported by roughly 30% of patients in some sources, so timely hydration strategies and clinician communication matter