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The average reduction in waist circumference was 18.4 cm in the tirzepatide group compared with 13.0 cm in the semaglutide group

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In June 2025, some GPs in England also started offering it to NHS patients who meet strict criteria: a BMI of 40 or over (or 37.5 if from a minority ethnic background) and four out of five of these conditions: type 2 diabetes, high blood pressure, heart and vascular disease, high cholesterol and obstructive sleep apnoea GPs in England have been incentivised to prescribe Mounjaro since April 2026, so that more people benefit from it

By gradually returning to healthier weight, tirzepatide will help to boost your self-esteem and confidence, and support improved mental health

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