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[DOI] [PubMed] [Google Scholar] 237.Ahern T., Tobin A.M., Corrigan M., Hogan A., Sweeney C., Kirby B

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Second, in humans with loss-of-function variants in SLC22A1, which decrease the uptake of metformin into the liver, the ability of metformin to lower A1c levels is not impaired (48)