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The more common ones include nausea, vomiting, diarrhea, and abdominal pain

In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)

If you notice worsening reflux, headaches, jitters, or dehydration when combining the two, consider adjusting your intake, switching to lowercaffeine alternatives, or spacing your doses more wisely

The compound tirzepatide dosage chart accounts for this, but compounded formulations may vary in potency between batches

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Obesity (Silver Spring) 14 (2), 194198 (2006)
