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Participants who reported food tasting sweeter after taking GLP-1s were twice as likely to report increased satiety, 67% more likely to report a reduction in appetite, and 85% more likely to report a reduction in food cravings

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Diabetologia 57 , 24752484 (2014)

17 Similarly, in a meta-analysis of 14 RCTs in T2DM patients conducted by Liu et al, tirzepatide was shown to provide superior HbA1c reduction and improved metabolic outcomes compared to placebo, insulin, and all other GLP-1 RAs at all doses examined

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Finally, we demonstrated that the coupling of MK-801 to GLP-1 effectively eliminates the unfavourable hyperlocomotive reaction to MK-801 in an open-field test (Fig