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Over-reliance on pharmacotherapy without adequate commitment to lifestyle interventions may obfuscate underlying etiologies

VESPER-3: the monthly maintenance experiment Pfizer describes VESPER-3 as an ongoing Phase 2b study evaluating monthly maintenance dosing in adults with obesity/overweight without type 2 diabetes

Most companies cover the drugs' use for managing Type 2 diabetes, and among respondents to the survey, 67% cover them for weight management

This phenomenon underscores the need for clinicians to monitor nutritional status and gut microbiome biomarkers

doi: 10.1016/j.clinre.2021.101794 88 SterniniCAnselmiLRozengurtE

Even a modest 610% weight reduction can significantly improve IIH outcomes [5]