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Pharmacokinetic data indicate that fasting plasma glucose (FPG) levels begin to decrease within two weeks, and steady-state plasma concentrations are typically achieved after six weeks of weekly dosing [59]

The effects of this presentation on weight and glycemia in clinical trials and real-world settings are comparable to those induced by the subcutaneous presentation, although a specific indication for weight control without DT2 is still lacking.86 In order to avoid confusion in daily clinical practice, it is important to note that liraglutide 3mg and semaglutide 2.4mg can be used in patients with DT2, provided these are obese or overweight with comorbidities

doi: 10.1038/s41573-021-00337-8

Patients often hear the brand names before they understand the differences

For those who want to be conservative, 30 days provides additional clearance buffer

PMCID: PMC8608955