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SGLT2 use was also associated with a slower annual rate of decline in eGFR, regardless of GLP-1 use at baseline

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There is no indication of medical efficacy or, in particular, weight loss

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doi: 10.1161/CIRCOUTCOMES.116.003497

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Yes, combining semaglutide with modest dietary improvements produces significantly better resultstypically 15-22% weight loss versus 10-15% with medication alone

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