glp-1 receptor agonist type 1 diabetes randomized trial Frontiers GLP-1 Receptor Agonists for Weight

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Adverse Effects Aside from the debated increased risk of DR progression, a separate complication that has garnered widespread attention is the purported association of semaglutide with an increased risk of NAION, a vision-threatening condition

2013, 108 (4): 365-10.1007/s00395-013-0365-x

References World Obesity Federation

You should expect that your odds of losing a lot of weight (we are somewhat arbitrarily defining that as 10% or more of your body weight) are no better than 50/50