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Its substrates also include pituitary adenylate cyclaseactivating polypeptides, insulinlike growth factor1, peptide YY, substance P, neuropeptide Y, gastrinreleasing polypeptides, and several chemokines, indicating its role in additional homeostatic functions, such as neurogenic inflammation, blood pressure control, and immune regulation [41]

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These two mechanisms support individuals living with type 2 diabetes in managing their blood glucose levels on a meal-to-meal basis

doi: 10.1111/acel.12427

Water and HFHS food were available ad libitum throughout the study period

They helped with weight loss, but once patients stopped using them, the lost weight invariably returned