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An excess in androgen synthesis in PCOS is caused by the abnormal response to elevated luteinizing hormone to folliclestimulating hormone (LH/FSH) ratio

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Why one needs an empty stomach and the other doesnt Semaglutide is a peptide

Drink plenty of water

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Semaglutide typically produces greater weight loss but has different side effects (mainly gastrointestinal symptoms like nausea), whereas orlistat causes oily stools and requires a lower-fat diet