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Physical activity: Regular exercise increases natural GLP-1 levels and improves insulin sensitivity

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Patient-reported outcomes data from clinical trials in Japanese patients indicated that patients considered less frequent injections more convenient and flexible (51) and that their use led to an improvement in quality of life, without compromising glycemic control (52)

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However, in a subgroup analysis of patients without esophageal varices, belapectin at 2 mg/kg did suppress HVPG and the development of varices (NCT02462967)

Researchers had hoped for modest improvements over existing therapies