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GLP-1 receptor activation is thought to reduce appetite, slow gastric emptying, and improve insulin secretion

That is going to change in a big way in the 1980s

Related Comparisons Semaglutide vs Tirzepatide Research indicates that Tirzepatide, a dual GIP/GLP-1 receptor agonist, demonstrates superior weight loss efficacy compared to Semaglutide, a GLP-1-only agonist, in head-to-head clinical trials

Am J Physiol Endocrinol Metab 290: E550E559, 2006

The agency didnt respond to a request for comment on the reports

Someone with a strong GLP1R signal might sustain results better on semaglutide alone, while a patient with GIPR-dominant hunger may benefit from GLP-Squared (semaglutide plus tirzepatide dual compound) before attempting discontinuation