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[15] Earlier reviews found some case reports during drug development and post-marketing surveillance

2016;11:e0166913

Takeda et al crossed Alzheimer transgenic mice (APP23) with two types of diabetic mice (ob/ob and NSY mice) and found a significant increase in IL-6 in the brains of hybrid mice fed with a high-fat diet
T2DM is the underlying cause of many complications, among which, cardiovascular diseases (CVDs) are mainly responsible for the high rates of morbidity and mortality

The statistical significance of each variable in the model differed depending on model formulation

10.1136/bmj.290.6471.811
