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Statistical analysis All statistical analyses were conducted using R (version 4.4.2), with the metafor package used for meta-analytic modeling

Highlights In this nationwide cohort study, initiating GLP1 RA as the firstline treatment was associated with improved 1year HbA1c levels compared with metformin

The dosage and frequency of administration can impact the overall cost of treatment

These findings underline GLP1s role in not only managing weight but also in decreasing heart attack and stroke risk- critical for East Valley patients facing hot summers and lifestyle stressors

Whether the advantages outweigh the drawbacks depends on the individuals medical history, goals, and how well they tolerate the medication

ACE inhibitors are a class of antihypertensive drugs, which is primarily used for the treatment of cardiovascular (e.g., congestive heart failure (CHF)), or renal diseases ( Wang et al