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Microdosing Tirzepatide A tirzepatide microdose is best defined as below the 2.5 mg starter, usually 0.5, 1.0, 1.5, or 2.0 mg weekly

Bioequivalence of JANUMET XR tablets with coadministered sitagliptin and extended-release metformin tablets has been demonstrated for all tablet strengths [see Clinical Pharmacology (12.3)]

One possible side effect that has been questioned is lower back pain

The GLP-1 receptor agonists approved for weight loss include: Zepbound (tirzepatide), Saxenda (liraglutide), and Wegovy (semaglutide)

Trial registration ClinicalTrials.gov NCT03136484

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