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Description
Centrally, GLP-1 promotes satiety through the activation of GLP-1 receptors in the hypothalamus and brainstem, which causes a reduction in food intake

Fung et al

Curcumin is a plant polyphenol compound found in turmeric root which has antioxidant, anti-inflammatory, hypoglycaemic and lipid-lowering properties

Interesing post Maam, This represents a fundamental shift in GLP-1 therapeutics---transitioning from complex biologics to scalable small molecules like Orforglipron with clear implications for cost, access, and global supply Interesting Great & Useful Initiative mem

December 2016

From a renal perspective, renal dosing thresholds vary between individual agents and prescribers must consult the relevant Summary of Product Characteristics (SmPC) for each medicine
