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Currently, this medicine is undergoing stage 3 clinical trials, which are expected to conclude in May 2026
However, in the end, if these changes are not made, true health benefits may not be realized, and the patient would need the medication indefinitely to manage their weight. But the promise is real

Constipation often improves as nausea fades (weeks 24), but it may persist as a low-grade side effect for 1020% of long-term users because GLP-1 naturally slows gut transit

JAMA Network Open, 6(5), e2314493

Winfrey said during the discussion that when she first heard about the growing popularity of drugs used for weight loss, she thought of them as "the easy way out." Speaking to People, Winfrey said the discussion with doctors led her to change her mind

Trulicity is administered through a once-weekly subcutaneous injection, designed with a user-friendly pen injector to simplify the process
