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Ultimately, the impaired ability to switch from lipid to carbohydrate oxidation under insulin-stimulated conditions leads to mitochondrial damage and dysfunction [58]

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Effects of the novel long-acting GLP-1 agonist, albiglutide, on cardiac function, cardiac metabolism, and exercise capacity in patients with chronic heart failure and reduced ejection fraction

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Common qualifying conditions include high blood pressure, type 2 diabetes, prediabetes, high cholesterol, obstructive sleep apnea, and cardiovascular disease