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3 Despite this limited direct action on the brain, semaglutide remains highly effective in reducing food intake and body weight, likely due to its peripheral actions and indirect influence on brain pathways

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The trial is due to end in May 2026

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The delayed gastric emptying primarily affects how quickly drugs are absorbed rather than the total amount absorbed, which may explain why clinically significant interactions are less common than initially feared

it only introduces confusion about which treatment deserves credit if something goes wrong
