leptin and glp 1 The gut microbiota regulates hypothalamic inflammation sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism: Cell Reports 🎤 One of the biggest

Theres a major gap in the GLP-1 literature where we dont know how midlife women in general respond to these drugs, she says

Wilson-Perez et al., 2013), a phenotype that goes against the role of GLP-1R signaling in the control of body weight

After discontinuation, any theoretical thyroid concerns diminish as the drug clears

Slow and steady loss is more sustainable

No research demonstrates that GLP-1 medications reduce thyroid antibody levels, slow autoimmune thyroid destruction, or improve thyroid function in patients with Hashimoto's disease

reported that GLP-2 analog GLP-2G genetically fused to protein polymers called XTEN has a greatly improved half-life (240 h) and lower dose requirements in a rat model of indomethacin-induced inflammation