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Daily injection with the weight-loss drug liraglutide was more effective than placebo (both combined with lifestyle interventions) at reducing weight in children 612 years of age with obesity.

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GLP-1RAs show modest SBP reductions (1.85.1 mmHg) and minimal DBP effects (~0.5 mmHg), though tirzepatide shows greater efficacy (~10.6 mmHg) in select populations