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NICE guidance also sets out which treatments are recommended, for whom and under what circumstances
In clinical trials investigating retatrutide, a dose-escalation approach has been used to minimise gastrointestinal side effects and improve tolerability

This includes evaluating the stability, scalability, and cost-effectiveness of different product options, ensuring they align with the long-term needs and goals of the plan and its members

However, insurance approval remains a hurdle

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Lu W, Wang S, Tang H, Yuan T, Zuo W, Liu Y
