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Description
This genome-wide reversal influences the common and cell type-specific pathways involved in aging and neurodegeneration

Current evidence suggests that benefitsboth glycemic control and weight reductionare maintained with continued treatment, but discontinuation frequently results in weight regain and worsening of metabolic parameters
Rapid weight loss also decreases bone density

doi: 10.1016/j.lfs.2017.11.019
(2020) 105:e25632571

The GLP-1R in Wnt1+ cells is required for the increase in plasma FGF21 levels following liraglutide treatment
