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doi: 10.1056/nejmoa2302392

Dual agonists that activate both GLP-1 and GIP receptors tend to cause these side effects slightly more frequently than pure GLP-1 agonists

Both medications are preferred options for diabetic patients with or at risk for cardiovascular disease
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Thus, the extent to which the gutbrain axis contributes to the incretin effect of GLP-1 remains to be determined

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