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OAD oral antidiabetics Systematic Reviews and Meta-analyses Four meta-analyses analyzed the metabolic outcomes of the combined therapy

Association of GLP-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases

The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board

Insulin concentration was measured using a radioimmunoassay kit (North Biological Technology Research Institute, Beijing, China)

1995;269:R222R225

Leeming, D
