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Needle phobia and injection anxiety Fear of needles is extremely common, affecting an estimated 20-30% of adults to some degree

When competitive pressure rises, net pricing may soften via increased rebates, creating a scenario where prescription growth does not translate 1:1 into net sales growth

Aggressive escalation (increasing dose every 2-3 weeks) sometimes produces faster early results but often leads to side effects that interrupt adherence

Premature conclusions lead to unnecessary medication changes and prolonged instability

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