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After two years (120 weeks), the patients retained roughly one-third of their original weight loss (5.6% of the original 17.3% loss)

Simpson SH, Majumdar SR, Tsuyuki RT, et al.: Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study

Brogden RN, Carmine AA, Heel RC, Speight TM, Avery GS

GLP-1 and GIP receptors are also present in thyroid C-cells, and animal studies have indicated an increased risk of medullary thyroid carcinoma with GLP-1RA treatment [43]

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43 Prevention of reactive oxygen species formation Excessive reactive oxygen species (ROS) may cause chronic inflammation and tissue damage