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Individuals who may warrant closer monitoring include: Those with a personal or family history of depression , anxiety, or other mood disorders People who have previously experienced mood changes on other weight-loss medications or GLP-1-based therapies Individuals with eating disorders or a complex relationship with food , for whom appetite suppression may have psychological implications (see NICE guideline NG69: Eating disorders: recognition and treatment) [10] Those experiencing significant life stressors alongside starting a new treatment People with poorly controlled type 2 diabetes , where fluctuating blood glucose levels both hypoglycaemia and hyperglycaemia can independently affect mood, concentration, and emotional wellbeing It is also worth acknowledging that obesity itself is associated with higher rates of depression and anxiety, and that the psychological experience of rapid body weight change whether positive or negative can be emotionally complex

Studies show weight loss surgery can also improve conditions caused by obesity, such as diabetes, sleep apnea, hypertension, and high cholesterol

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Sometimes you forget your injection, or a flight delay keeps you away from your medication

Recientemente en un modelo de roedores con diabetes e hipertensin arterial se evidenci que la administracin crnica de GLP-1 mejoraba la sobrevida y preservaba la funcin cardaca (47)