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Guest Sean Hashmi, MD The Permanente Federation Podcast transcript Transcript is autogenerated

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In 2016, more than 100,000 people died from opioid overdose, most likely from respiratory depression
Meanwhile, Holst et al
Retatrutide is a synthetic triple agonist peptide targeting glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously, representing the next generation of incretin-based research compounds beyond dual agonists

A drug that silences hunger had gone viral