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Due to the bodys natural tendency to restore its former weight, many people regain their lost weight when they stop using GLP-1 drugs.

The survival benefit was more pronounced in younger people and those with cardiometabolic comorbidities, highlighting the need for a careful riskbenefit evaluation when prescribing GLP-1 RAs in high-risk individuals.

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Smaller meals, hydration, slower dose increases, and better timing can often reduce it.

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