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We first interrogated the effect of dulaglutide in the absence and then in the presence of rolipram, a phosphodiesterase 4 inhibitor, on the beating rate in mouse right atrial preparations

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Less commonly prescribed for weight management compared to semaglutide and tirzepatide

The actions of GLP-1 to stimulate insulin and inhibit glucagon secretion, together with its inhibitory effects on food intake and gastric emptying, spurred considerable effort in development of GLP-1based therapeutics