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This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 12 digital issues and online access to articles $119.00 per year only $9.92 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout References Alzheimers Association

Many individuals gain weight due to emotional eating patterns or the habit of using food for comfort

They also improve overall health

Studies on other addictive drugs are needed

Crash diets frequently reduce: Water weight Glycogen stores Muscle mass What they dont always achieve is meaningful improvement in visceral fat levels

4,26 Findings from certain studies suggest that GLP-1 has direct effects on the liver, adipose tissue and skeletal muscle and whether GLP-1R is expressed in these tissues is currently debated