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If you develop signs of methotrexate toxicitymouth sores, severe diarrhea, or elevated liver enzymesyour provider may need to hold or reduce methotrexate while your body stabilizes, even if semaglutide dosing is otherwise appropriate

While it has many benefits, it is important to monitor for potential side effects, including heart palpitations

2016 doi: 10.1165/rcmb.2015-0311OC

Epidemiological evidence suggests an elevated risk of dementia among individuals with T2DM

There are videos on these pages for you to listen to about what you receive and how you can access them on-demand, in your own time

TRIUMPH-4 weight loss results at 68 weeks Source: Eli Lilly press release, December 2025