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GLP-1 receptor agonists GLP-1 became the focus of incretin therapy because of its strong potentiation of glucose-induced insulin secretion and glucose-lowering efficacy in type 2 diabetes

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Journal of Medicinal Chemistry, 67 (1), 180198.

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However, a national Blue Health Intelligence study from the Blue Cross Blue Shield Association finds that more than 30% of patients dropped out of treatment after the first four weeks and 58% of patients taking the medications for weight loss discontinued use before seeing a clinical benefit