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"As part of an extension trial published a year later, participants regained an average of two-thirds of the weight they shed within 12 months of discontinuing the drug." Within 12 months of discontinuing the drug, participants regained an average of two-thirds of the weight they shed

Ikonomidis I, Pavlidis G, Thymis J, Birba D, Kalogeris A, Kousathana F, et al

These groups were evaluated on how the effect of GLP-1 had on apoptosis

This can also be seen after gall bladder removal surgery and I wonder if patients with diarrhea on retatrutide wouldnt benefit from psyllium husk fiber(aka Metamucil in the USA) or taking low doses of drugs called bile acid sequestrants until their GI can adjust to the retatrutide

Setting Claims data from Medicare and two large commercial insurance databases in the United States from April 2013 to April 2022

Be honest and complete when providing this information even distant family history of unusual endocrine conditions may be relevant