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Provider monitoring helps distinguish normal adaptation from true intolerance

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Effects on glucose metabolism Increased insulin secretion in a glucose-dependent manner Decreased glucagon secretion Increased insulin sensitivity Possible decrease in blood glucose due to the above-mentioned effects

"Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA." The Lancet
